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Tramadol is a synthetic opioid given by mouth in the form of a tablet, capsule, or compounded liquid, and is used off label to treat pain. Common side effects include sedation, gastrointestinal upset, or agitation. It should not be used in pets that are hypersensitive to opioids, and should be used cautiously in geriatric, sick, or pets with seizures. If a negative reaction occurs, call your veterinary office.