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  • Paroxetine is given by mouth and is used off label to treat certain behavior disorders such as aggression, anxiety, and urine-marking. Give as directed by your veterinarian. Common side effects include sleepiness and decreased appetite. Do not use in pets that are allergic to it or other SSRIs, or pets currently taking MAOIs. If a negative reaction occurs, please call your veterinary office.

  • Parvovirus may affect dogs of all ages but is most common in unvaccinated dogs less than one year of age. Young puppies under five months of age are usually the most severely affected and difficult to treat. Clinical signs can vary but generally include severe vomiting and diarrhea; the diarrhea often has a powerful smell, may contain lots of mucus, and may or may not contain blood. Most dogs with CPV infection recover if aggressive treatment is used and if therapy is started before severe septicemia and dehydration occur.

  • Patent ductus arteriosus (PDA) is a heart defect that occurs when the ductus arteriosus (an opening between the aorta and the pulmonary artery) fails to close at birth. A PDA is usually diagnosed when your veterinarian hears a continuous heart murmur during a routine physical examination of your puppy. This article explains PDA and discusses signs, treatment, and prognosis for this condition.

  • Pemphigus is an autoimmune skin disease in which the body's immune system attacks the connections between its own skin cells. The three most common types of pemphigus are pemphigus foliaceus, pemphigus vulgaris, and pemphigus erythematosus. Treatment requires suppression of the immune system and prognosis varies depending on the type.

  • Penetrating wounds can look minor on the surface but may cause severe injury below the skin. A thorough assessment requires sedation or anesthesia and surgery may be required to address the extent of the injury. This handout outlines first aid steps a pet owner can take while transporting their injured pet to the veterinary hospital.

  • Penicillin G (brand names VetriPen G, PenOne Pro, others), is an antibiotic used to treat susceptible infections in cats, dogs, chickens, horses, livestock, ferrets, hedgehogs, rabbits, and other animals. It is used off label (extra label) in cats, dogs, and other companion animals. Penicillin G comes in injectable suspension form. Caution when using in rabbits and other animals sensitive to penicillin-like drugs.

  • A Penrose drain is a latex tube placed into a wound with one or two ends exiting the skin to passively remove unwanted fluid, usually from abscesses or open wounds. This handout provides post-operative wound care instructions for dogs sent home with a Penrose drain.

  • Pentosan polysulfate sodium is an injectable disease-modifying osteoarthritis drug (DMOAD) used to treat non-infectious and traumatic arthritis in dogs. It is also used off-label in cats. Follow your veterinarian’s instructions on how to administer the injection and dispose of the needle and syringe appropriately. Side effects are rare when given according to label recommendations and at prescribed intervals. Do not use in pets with a known hypersensitivity to it, in pets with known or suspected bleeding disorders or immune-mediated arthritis, or in pets with severe kidney or liver disorders.

  • Pentoxifylline is given by mouth and is used off label to treat skin disorders and poor perfusion due to inflamed blood vessels. Give as directed. Common side effects include vomiting, diarrhea, lack of appetite, excitement, or restlessness. Do not use in pets that are allergic to it, allergic to xanthines, or in pets with bleeding in the brain or eye. If a negative reaction occurs, please call your veterinary office.

  • Perianal fistula, also known as anal furunculosis is a serious medical condition that most commonly affects German Shepherd dogs. Perianal fistulas are characterized by chronic, purulent, smelly, ulcerating, sinus tracts in the anal region and surrounding skin. More recent studies indicate that the condition is more likely caused by an autoimmune disease. Medical management with immune-modulating drugs is now the preferred therapy. In severe cases, surgery is required to debride or remove as much infected tissue as possible.